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Cyproterone acetate (Androcur®, Cyprostat®) is an antiandrogen, i.e. it suppresses a actions of testosterone (or like its metabolite dihydrotestosterone) on tissues. It acts by blocking a testosterone receptor. Its independent indications come prostate cancer, benign prostatic hyperplasia, priapism, hypersexuality and other conditions where androgenic hormone action maintains a disease run.
Until a development of leuprolide, cyproterone was one of the pack doses utilized to handle precocious puberty. It was besides utilized around carnal experimentation to investigate a actions of androgenic hormone around foetal sexual differentiation.
Additionally, its acetate form (cyproterone acetate) has progestational activity (e.g. it acts rather progesterone). When section of occasionally contraceptive pills (Diane®) it decreases acne and hirsutism (male-pattern hair growth).
Side-results within men include gynecomastia (breast gl& hypertrophy) and galactorrhea (milk outflow). Erectile dysfunction is a direct effect of its mode of action.
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